Abstracts Book for Pancreas 2018, Innovations in the Care of Pancreatic Cancer
Glad to announce that the Abstracts for the international conference Pancreas 2018, Innovations in the Care of Pancreatic Cancer to be held at Johns Hopkins Medical Campus, Baltimore, Maryland, April 26-29, 2018 have been published on the journal Annals of Pancreatic Cancer(APC).
All the abstracts now are open to readers.
Abstract
AB001. S001. Defining DDR deficiency and replication stress in pancreatic cancer
Stephan B. Dreyer, Viola Paulus-Hock, Eirini Lampraki, Rosie Upstill-Goddard, Giuseppina Caligiuri, Holly Brunton, Bryan Serrels, Richard Cunningham, Nigel B. Jamieson, Colin J. McKay, Andrew V. Biankin, Peter J. Bailey, David K. Chang
Abstract
AB002. S002. Wild-type KRAS allele exerts its tumorsuppressive function through decreased Yap1 activation in pancreatic cancer
Han Yan, Chih-Chieh Yu, Stuart A. Fine, Ayman Lee Youssorf, Dario Garcia-Carracedo, Dillon C. Carg, Edwin Cheung, Wei-Yann Tsai, Ji Luo, Yi Miao, Wanglong Qiu, Gloria H. Su
Abstract
AB003. S003. BRCA1/BRCA2 germline mutation carriers and sporadic pancreatic adenocarcinoma
Alex B. Blair, Vincent P. Groot, Georgios Gemenetzis, Jishu Wei, John L. Cameron, Matthew J. Weiss, Michael Goggins, Christopher L. Wolfgang, Jun Yu, Jin He
Abstract
AB004. S004. Differences in cancer metabolism between subtypes of pancreatic ductal adenocarcinoma (PDAC) are associated with survival and offer therapeutic opportunities
Frederike Dijk, Eline C. Soer, Johannes B. Halfwerk, Gerrit K. Hooijer, Veronique L. Veenstra, Lan Zhao, Olivier R. Busch, Marc C. Besselink, Lennart B. van Rijssen, Hanneke W. Wilmink, Hanneke W. van Laarhoven, Jan Koster, Xin Wang, Maarten F. Bijlsma, Joanne Verheij, Marc J. van de Vijver
Abstract
AB005. S005. A multiinstitutional postoperative nomogram for disease recurrence following resection of localized G1/G2 pancreatic neuroendocrine tumors
Alessandra Pulvirenti, Joanne F. Chou, Chiara Nessi, Sara Cingarlini, Michael I. D’Angelica, T. Peter Kingham, Vinod P. Balachandran, Luca Landoni, William R. Jarnagin, Roberto Salvia, Peter J. Allen, Claudio Bassi
Abstract
AB006. S006. Variation in longterm oncologic outcomes by types of cancer center accreditation: an analysis of a SEER-Medicare population with pancreatic cancer
Zhi Ven Fong, David Chang, Carlos Fernandezdel Castillo, Cristina Ferrone, Ginger Jin, Angela Tramontano, Chin Hur, Andrew Warshaw, Keith Lillemoe Motaz Qadan
Abstract
AB007. S007. Survival in locally advanced pancreatic cancer: impact of surgical resection after neoadjuvant therapy
Georgios Gemenetzis, Vincent Groot, Alex Blair, John Cameron, Richard Burkhart, Matthew Weiss, Christopher Wolfgang, Jin He
Abstract
AB008. S008. Diagnostic yield of intraoperative pancreatoscopy for the investigation of pancreatic IPMN
Roberto Valente, Urban Arnelo, Marcus Reuterwall Hansson, Zeeshan Ateeb, Miroslav Vujasinovic, Asif Halimi, Chiara Maria Scandavini, Matthias Lohr, Marco Del Chiaro
Abstract
AB009. S009. Effect of endoscopic iodine 125 seeds brachytherapy on advanced pancreatic cancer: experience of single center
Bin Xiao, Guo-Sheng Chen, Yun-Peng Peng, Kui- Rong Jiang, Yi Miao
Abstract
AB010. S010. Pancreatic cystic lesions’ follow-up with abdominal ultrasound scan: could it play an alternative role to the routine use of MRI?
Bin Xiao, Guo-Sheng Chen, Yun-Peng Peng, Kui- Rong Jiang, Yi Miao
Abstract
AB011. S011. Mesenchymal pancreatic cancer cells inhibit pancreatic stellate cell activation
Madelaine van Mackelenbergh, Anne Steins, J. W. Wilmink, Hanneke W. van Laarhoven, Maarten F. Bijlsma
Abstract
AB012. S012. Immunophenotypes of pancreatic ductal adenocarcinoma
Ines de Santiago, Christopher Yau, Mark Middleton, Michael Dustin, Florian Markowetz, Shivan Sivakumar
Abstract
AB013. S013. Towards early detection of pancreatic cancer: applying NGS in the clinical setup
Merav Ben Yehoyada, Erez Scapa, Oren Shibolet, Erwin Santo, Guy Rosner
Abstract
AB014. S014. Fractional uptake of circulating tumor cells across liver-lung compartments during resections of periampullary cancer aimed at cure
Cecilia Engström, Caroline Vilhav, Peter Naredi, Johan Bourghardt-Fagman, Britt-Marie Iresjö, Kent Lundholm
Abstract
AB015. S015. Circulating tumor cells dynamics in pancreatic adenocarcinoma correlate with disease status: data from a prospective trial
Georgios Gemenetzis, Vincent Groot, Jun Yu, Ding Ding, Jonathan Teinor, Ammar Javed, Laura Wood, Richard Burkhart, John Cameron, Jin He, Christopher Wolfgang
Abstract
AB016. S016. Lymphadenectomy in resected node-negative pancreatic cancer: are some patients being understaged?
Jad Abou Khalil, Margaret Mandelson, Scott Helton, Adnan Alseidi, Thomas Biehl, Vincent Picozzi, Bruce Lin, Flavio Rocha
Abstract
AB017. S017. Is main pancreatic duct dilation really an independent risk factor for malignancy in main-duct and combined-IPMNs?
Francesca Aleotti, Stefano Crippa, Alessandra Piccioli, Enrico Longo, Francesca Di Salvo, Marco Schiavo Lena, Maria Chiara Petrone, Gianpaolo Balzano, Paolo Arcidiacono, Corrado Rubini, Giuseppe Zamboni, Claudio Doglioni, Massimo Falconi
Abstract
AB018. S018. The prognostic impact of primary tumor resection in pancreatic neuroendocrine tumors with synchronous multifocal liver metastases
Xiafei Hong, Wenming Wu, Hongmei Dai, Chen Lin, Xianze Wang, Haiyu Pang, Peiran Xu, Jialin Jiang, Yupei Zhao
Abstract
AB019. S019. Pancreatectomy plus arterial resection is superior to palliation in patients with locally advanced PDAC
Marco Del Chiaro, Elena Rangelova, Asif Halimi, Zeeshan Ateeb, Chiara Scandavini, Roberto Valente, Lars Lundell, Ralf Segersvard, Urban Arnelo
Abstract
AB020. S020. Importance of adjuvant hepatic arterial infusion chemotherapy using high-dose 5-fluorouracil with systemic gemcitabine for resectable pancreatic cancer
Kota Nakamura, Akahori Takahiro, Minako Nagai, Satoshi Nishiwada, Kenji Nakagawa, Toshihiro Tanaka, Hideyuki Nishiofuku, Kimihiko Kichikawa, Naoya Ikeda, Masayuki Sho
Abstract
AB021. S021. Expression patterns and clinical implications of immunotherapy targets PD-1, PD-L1 and CD163 in undifferentiated carcinoma of the pancreas with osteoclastlike giant cells
Claudio Luchini, Jerome Cros, Antonio Pea, Camilla Pilati, Nicola Veronese, Borislav Rusev, Paola Capelli, Andrea Mafficini, Alessia Nottegar, Lodewijk A. A. Brosens, Michaël Noë, G. Johan A. Offerhaus, Peter Chianchiano, Giulio Riva, Paola Piccoli, Claudia Parolini, Giuseppe Malleo, Rita T Lawlor, Vincenzo Corbo, Nicola Sperandio, Mattia Barbareschi, Matteo Fassan, Liang Cheng, Laura D. Wood, Aldo Scarpa
Abstract
AB022. S022. A continuous clonal labeling method to reveal growth dynamics in developing, adult and injured pancreas
Sophie C. Lodestijn, Lisanne E. Nijman, Maria Lecca, Douglas J. Winton, Maarten F. Bijlsma, Louis Vermeulen
Abstract
AB023. S023. Identification and targeting of a poor-prognosis subgroup of pancreatic cancer
Veronique Veenstra, Frederike Dijk, Eline Soer, Lan Zhao, Johannes Halfwerk, Gerrit Hooijer, Naomi Donner, Helene Damhofer, Marco Marzano, Anne Steins, Cynthia Waasdorp, Olivier Busch, Marc Besselink, Johanna Tol, Lieke Welling, L. Bengt van Rijssen, Hanneke Wilmink, Hanneke van Laarhoven, Jan Paul Medema, Louis Vermeulen, Sander van Hooff, Jan Koster, Joanne Verheij, Marc van de Vijver, Xin Wang, Maarten Bijlsma
Abstract
AB024. S024. Drug responses of patient-derived cell lines in vitro that match drug responses of patient PDAc tumors in situ
Kaitlin Lindenburger, Jason Link, Nicholas Kendsersky, Michael Cadell, Seema Agarwal, David Sauer, Christian Lanciault, Charles Lopez, Erin Gilbert, Rosalie Sears, Brett Sheppard
Abstract
AB025. S025. Basement membrane destruction by pancreatic stellate cells leads to local invasion in pancreatic ductal adenocarcinoma
Kazuhiro Koikawa, Kenoki Ohuchida, Yohei Ando, Shin Kibe, Hiromichi Nakayama, Shin Takesue, Sho Endo, Toshiya Abe, Takashi Okumura, Chika Iwamoto, Koji Shindo, Taiki Moriyama, Kohei Nakata, Yoshihiro Miyasaka, Takao Ohtsuka, Eishi Nagai, Kazuhiro Mizumoto, Makoto Hashizume, Masafumi Nakamura
Abstract
AB026. S026. What is the optimal surgical strategy for grade-C pancreatic fistula after pancreaticoduodenectomy? A large retrospective multicenter study
Tao Ma, Xueli Bai, Wen Chen, Gang Jin, Deliang Fu, Renyi Qin, Wenhui Lou, Kuirong Jiang, Chenghao Shao, Yinmo Yang, Heshui Wu, Guogang Li, Yinan Shen, Tingbo Liang
Abstract
AB027. S027. Factors associated with invasive intraductal papillary mucinous carcinoma
Seiko Hirono, Manabu Kawai, Ken-ichi Okada, Motoki Miyazawa, Yuji Kitahata, Ryohei Kobayashi, Akio Yanagisawa, Hiroki Yamaue
Abstract
AB028. S028. Risk of the serous cystic neoplasms in pancreas results from no surgical intervention: a multi-center retrospective study
Ning Pu, Ji Li, Gang Li, Xin Wang, Gang Zhao, Lei Wang, Xiaodong Tian, Chunhui Yuan, Kuirong Jiang, Jun Cao, Xiaowu Xu, Xueli Bai, Yongsheng Yang, Fubao Liu, Xuewei Bai, Rui Kong, Zheng Wang, Wenhui Lou, Wenchuan Wu
Abstract
AB029. S029. Neoadjuvant therapy offers longer survival than upfront surgery for poorly differentiated and higher stage pancreatic cancer
Hanna Seppanen, Anna Nurmi, Harri Mustonen, Helka Parviainen, Katriina Peltola, Caj Haglund
Abstract
AB030. S030. Defining and predicting early recurrence in 957 patients with resected pancreatic ductal adenocarcinoma
Vincent P. Groot, Georgios Gemenetzis, Alex B. Blair, Roberto J. Rivero-Soto, Jun Yu, Ammar A. Javed, Richard A. Burkhart, Inne H. M. Borel Rinkes, I. Quintus Molenaar, John L. Cameron, Matthew J. Weiss, Christopher L. Wolfgang, Jin He
Abstract
AB031. P001. The value of infectious biomarkers for prediction of complication after pancreatic surgery
Yuan Fang, Wenchuan Wu, Dansong Wang, Tiantao Kuang, Xuefeng Xu, Wenhui Lou
Abstract
AB032. P002. Radiomics based classification of pancreatic cystic neoplasms
Linda Chu, Seyoun Park, Elliott Fishman
Abstract
AB033. P003. Identification of germline mutations in cancer predisposition genes in patients with a personal and/or family history of pancreatic cancer
Greet Wieme, Bruce Poppe, Toon Rosseel, Kim De Leeneer, Kathleen Claes
Abstract
AB034. P005. What is the role of central pancreatectomy in pancreatic surgery? —a systematic review and metaanalysis
Weidong Xiao, Jisheng Zhu, Long Peng, Le Hong, Gen Sun, Yong Li
Abstract
AB035. P006. Activity of heat shock protein-90 (HSP90) inhibitors against pancreatic cancers grown in 3 dimensions
Aiste Gulla, Hong Liang, Egidijus Kazlauskas, Daumantas Matulis, Kestutis Strupas, James R. Eshleman
Abstract
AB036. P007. BM-derived cells differentiated into multilineage hematopoietic cells regulate invasion and proliferation of pancreatic cancer
Chika Iwamoto, Kenoki Ohuchida, Takashi Okumura, Kazuhiro Koikawa, Shin Takesue, Hiromichi Nakayama, Sho Endo, Shin Kibe, Yohei Ando, Koji Shindo, Kohei Nakata, Kohta Miyawaki, Masaharu Murata, Koichi Akashi, Masafumi Nakamura, Makoto Hashizume
Abstract
AB037. P008. Intratumoral regulatory T cells (Tregs) reduced by neutralization TGF-β in murine pancreatic ductal adenocarcinoma model without promising functional change
Guochao Zhao, Ning Pu, Abulimiti Nuerxiati, Hanlin Yin, Lei Zhang, Wenhui Lou, Wenchuan Wu
Abstract
AB038. P009. Tyrosine kinases and their prognostic value in digestive tract cancers
Guodong Shi, Jingjing Zhang, Zipeng Lu, Kuirong Jiang, Yi Miao
Abstract
AB039. P010. Use GeCKO lentiviral pooled libraries screen to identify genes which contribute to chemoresistance of pancreatic cancer
Hai Yang, Christian Pilarsky
Abstract
AB040. P011. Prognostic and diagnostic value of REG4 serum and tissue expression in pancreatic ductal adenocarcinoma
Hanna Seppanen, Kapo Saukkonen, Jaana Hagström, Harri Mustonen, Laura Lehtinen, Olli Carpen, Leif C. Anderrson, Caj Haglund
Abstract
AB041. P012. The effect of pancreatic cancer patient derived serum on macrophage M1/M2 polarization
Matilda Juusola, Harri Mustonen, Markus Vähä-Koskela, Pauli Puolakkainen, Hanna Seppanen
Abstract
AB042. P013. LncRNAPTCHD3P1 enhances chemosensitivity of gemcitabine in pancreatic cancer and inhibits cancer cell proliferation and metastasis via inhibiting Warburg effect
Jiabei Wang, Keyu Li
Abstract
AB043. P014. Genomic characterization of pancreatic cancer in Chinese population
Wentao Gao, Kai Zhang, Zipeng Lu, Jishu Wei, Junli Wu, Feng Guo, Jianmin Chen, Chunhua Xi, Min Tu, Lei Tian, Kuirong Jiang, Yi Miao
Abstract
AB044. P015. Clinicopathological relevance of SMAD4 and RUNX3 in pancreatic cancer
AB044. P015. Clinicopathological relevance of SMAD4 and RUNX3 in pancreatic cancer
Abstract
AB045. P016. Profile of neoepitopes on human pancreas tumor tissue by proteomics
Kenji Fujiwara, Pingbo Zhang, Lei Zheng
Abstract
AB046. P017. Identification of pathological ampullary adenocarcinomas subtypes and their prognosis using the immunohistochemical score of CDX2, CK7 and CK 20
Matteo Palmeri, Luca Pollina, Niccola Funel, Niccolò Furbetta, Gregorio Di Franco, Simone Guadagni, Desirée Gianardi, Matteo Bianchini, Leonardo Rossi, Enrico Vasile, Alfredo Falcone, Giulio Di Candio, Marco Del Chiaro, Franco Mosca, Luca Morelli
Abstract
AB047. P018. A technical refinement of the pancreaticojejunostomy after pancreatoduodenectomy (PD): the pancreas encompassing jejunal anastomosis (PEJA)
Alfonso Recordare, Roberto Moretti, Guido Meneghetti, Fabrizio Cimino, Livio Baiano, Francesco Fiumara, Maurizio Romano, Giovanni Pirozzolo, Maurizio Rizzo
Abstract
AB048. P019. Middle segment pancreatectomy: the complications and safety
Baobao Cai, Zipeng Lu, Junli Wu, Wentao Gao, Jianmin Chen, Feng Guo, Jishu Wei, Cuncai Dai, Kuirong Jiang, Yi Miao
Abstract
AB049. P020. Robotic pancreatoduodenectomy: results of the first twenty procedures
Carolijn Nota, Inne Borel Rinkes, Livia de Guerre, Hjalmar van Santvoort, Wouter Te Riele, Melissa Hogg, Herbert Zeh, Jeroen Hagendoorn, Quintus Molenaar
Abstract
AB051. P022. Vein invasion in pancreatic adenocarcinoma is a topography: vein resection in pancreaticoduodenectomy is worthy while
Chunlu Tan, Xubao Liu, Keyu Li
Abstract
AB052. P023. Diagnosis and management of postpancreatectomy hemorrhage: a systematic review and meta-analysis
Floortje van Oosten, F. Jasmijn Smits, Hjalmar C. van Santvoort, I. Quintus Molenaar
Abstract
AB053. P024. Ki-67 proliferative index in resectable pancreatic ductal adenocarcinoma: does it have a prognostic role?
Francesca Aleotti, Ilaria Pergolini, Stefano Crippa, Michele Pagnanelli, Giulio Belfiori, Alessandro Pucci, Stefano Partelli, Corrado Rubini, Paola Castelli, Giuseppe Zamboni, Massimo Falconi
Abstract
AB054. P025. Impact of pasireotide on post-operative pancreatic fistulas after pancreatic distal resections
Hanna Seppänen, Tiina Vuorela, Harri Mustonen, Caj Haglund
Abstract
AB055. P026. Prediction of clinically relevant pancreatic fistula in the early phase after distal pancreatectomy
Hideaki Iwama, Kazuhiro Suzumura, Etsuro Hatano, Toshihiro Okada, Yasukane Asano, Naoki Uyama, Ikuo Nakamura, Seikan Hai, Kenjiro Iida, Jiro Fujimoto
Abstract
AB056. P027. Preoperative chemotherapy for resectable pancreatic cancer improves prognosis of node positive pancreatic head cancer
Hidehiro Tajima, Mitsuyoshi Okazaki, Takahisa Yamaguchi, Shinichi Nakanuma, Isamu Makino, Tomoharu Miyashita, Hiroyuki Takamura, Tetsuo Ohta
Abstract
AB057. P029. Rescue ERCP with pancreatic stent replacement against post- ERCP pancreatitis following prophylactic pancreatic stent placement
Hiroyuki Hisai, Tamaki Sakurai, Yutaka Koshiba, Natsumi Yamauchi, Saki Natsumi, Etsu Miyazaki
Abstract
AB058. P030. The 8th versus the 7th edition of the AJCC Cancer Staging Manual in predicting the prognosis of pancreatic ductal adenocarcinoma
Hongyu Chen, Keyu Li, Xubao Liu
Abstract
AB059. P031. Outcomes of pylorus-preserving versus conventional pancreaticoduodenectomy in the era of enhanced recovery: a single-institution experience
Jad Abou Khalil, Thomas Biehl, Adnan Alseidi, Flavio Rocha, Scott Helton
Abstract
AB060. P032. 2,029 cases of Whipple’s procedure: 12-year experience from a single center
Jiang Kuirong, Cuncai Dai, Junli Wu, Wentao Geo, Qiang Li, Bin Xiao, Feng Guo, Jianmin Chen, Jishu Wei, Zipeng Lu, Min Tu, Baobao Cai, Pengfei Wu, Jie Yin, Yong Gao, Hao Gao, Yi Miao
Abstract
AB061. P033. A comparison of delayed gastric emptying and nutritional status after pylorus-preserving versus stomach-preserving pancreaticoduodenectomy
Kazuhiro Suzumura, Etsuro Hatano, Toshihiro Okada, Yasukane Asano, Naoki Uyama, Ikuo Nakamura, Seikan Hai, Masaharu Tada, Hideoaki Sueoka, Kenjiro Iida, Hideaki Iwama, Hiroshi Nishida, Jiro Fujimoto
Abstract
AB062. P034. Prior cholecystectomy and the survival of resected pancreatic cancer: a single-center retrospective cohort in Chinese population
Lingdi Yin, Xinchun Liu, Tongtai Liu, Yunpeng Peng, Kai Zhang, Wentao Gao, Junli Wu, Kuirong Jiang, Jishu Wei, Yi Miao
Abstract
AB063. P035. Radiofrequency ablation and irreversible electroporation in locally advanced pancreatic cancer: competitive or complementary treatment modalities?
Marieke Walma, Jantien Vogel, Eran van Veldhuisen, Olivier Busch, Hanneke Wilmink, Hjalmar van Santvoort, Marc Besselink, Quintus Molenaar, Krijn van Lienden
Abstract
AB064. P036. Fat tissue and pancreatic parenchyma play different roles in pancreatic cancer invasion
Kenoki Ohuchida, Shin Kibe, Takashi Okumura, Koji Shindo, Taiki Moriyama, Kohei Nakata, Yoshihiro Miyasaka, Takao Ohtsuka, Masafumi Nakamura
Abstract
AB065. P037. Prognostic role of the parenchymal frozen transection margin during pancreaticoduodenectomy (PD) for ductal pancreatic adenocarcinoma
Francesca Aleotti, Giovanni Guarneri, Stefano Crippa, Domenico Tamburrino, Stefano Partelli, Gianpaolo Balzano, Claudio Doglioni, Corrado Rubini, Giuseppe Zamboni, Michele Pagnanelli, Alessandro Fogliati, Giulia Gasparini, Massimo Falconi
Abstract
AB066. P038. HHLA2 is overexpressed in pancreatic ductal adenocarcinoma and precancerous lesions
Han Yan, Ji-Shu Wei, Wanglong Qiu, Helen E. Remotti, Min Tu, Chun-Hua Xi, Ye-Ran Yang, Yun-Peng Peng, Wei-Yann Tsai, Yi Miao, Gloria H. Su
Abstract
AB067. P039. Rab37 mediates exosomal osteopontin secretion to promote pancreatic cancer metastasis and stemness
Yan-Shen Shan
Abstract
AB068. P040. Heterotopic ossification in abdominal surgery incisions as an independent predictor of prognosis of malignant abdominal tumors: a casecontrol study from a single institution
Jishu Wei, Tongtai Liu, Haihua Zou, Kai Zhang, Xinchun Liu, Qing Xu, Yi Miao
Abstract
AB069. P041. A nomogram based on postoperative neutrophil-to-lymphocyte rate and TNM stage to predict the prognostic value in pancreatic ductal adenocarcinoma with open distal pancreatosplenectomy
Ning Pu, Hanlin Yin, Jian-ang Li, Guochao Zhao, Yadong Xu, Abulimiti Nuerxiati, Dansong Wang, Xuefeng Xu, Tiantao Kuang, Dayong Jin, Wenhui Lou, Wenchuan Wu
Abstract
AB070. P042. Serum protein profile in IPMN
Hanna Seppanen, Heini Nieminen, Mayank Saraswat, Sakari Joenväärä, Ari Ristimäki, Caj Haglund, Risto Renkonen
Abstract
AB071. P043. TLR1 predicts favorable prognosis in young pancreatic cancer patients
Hanna Seppanen, Mira Lanki, Jaana Hagström, Harri Mustonen, Caj Haglund
Abstract
AB072. P044. Analyses of aberrant methylation of tumor suppressive miRNAs in the patients with pancreaticobiliary diseases in bile juice
Koushiro Ohtsubo, Kaname Yamashita, Kunio Miyake, Seiji Yano
Abstract
AB073. P045. Mutant GNAS drives pancreatic tumorigenesis via PKA-SIK signaling and reprogramming lipid metabolism
Krushna Patra, Yasutaka Kato, Yusuke Mizukami, Andrew S. Liss, Robert A. Screaton, Wilhelm Haas, Mari Mino-Kenudson, Carlos Fernandez-Del Castillo, Nabeel Bardeesy
Abstract
AB074. P046. Comprehensive analysis of links between diabetes and pancreatic cancer: a bioinformatical approach
Zipeng Lu, Lingdi Yin, Guangfu Wang, Yunpeng Peng, Nan Lv, Kai Zhang, Yi Miao
Abstract
AB075. P047. Human pancreatic stellate cells secreted fibronectin promote chemoresistance to gemcitabine in PDAC
Manoj Amrutkar, Daniela Lenggenhager, Caroline S. Verbeke, Ivar P. Gladhaug
Abstract
AB076. P048. Microsatellite instability and tumor volume inversely affect early progression free survival in adjuvant setting of patients with pancreatic ductal adenocarcinoma: lights and shadows of molecular pathology and immunotherapy
Matteo Palmeri, Niccola Funel, Luca Pollina, Gregorio Di Franci, Simone Guadagni, Niccolò Furbetta, Desirée Gianardi, Matteo Bianchini, Virginia Coli, Manuel Gentiluomo, Daniele Campa, Enrico Vasile, Lorenzo Fornaro, Silvia Catanese, Giulio Di Candio, Alfredo Falcone, Franco Mosca, Luca Morelli
Abstract
AB077. P049. Genetic relationship of pancreatic ductal adenocarcinoma and co-occurring IPMN
Matthaus Felsenstein, Michael Noe, David Masica, Waki Hosada, Peter Chianchiano, Cathy Guerra, Gemma Lionheart, Lodewijk Brosens, Antonio Pea, Jun Yu, Georgios Gemenetzis, Vincent Groot, Martin Makary, Jin He, Matthew Weiss, John Cameron, Christopher Wolfgang, Ralph Hruban, Nicholas Roberts, Rachel Karchin, Michael Goggins, Laura Wood
Abstract
AB078. P050. Efficacy of integrated immune ratio associated with tumor growth and prognosis in pancreatic cancer
Ning Pu, Guochao Zhao, Wenhui Lou, Wenchuan Wu
Abstract
AB079. P051. Blockage of CTR1-dependent copper absorption increases autophagy to resist apoptosis of pancreatic ductal carcinoma cells
Sheng Tai, Chun-Bo Teng
Abstract
AB080. P052. Role of neutrophil extracellular traps (NETs) in pancreatic cancer liver metastasis
Shin Takesue, Kenoki Ohuchida, Hiromichi Nakayama, Kazuhiro Koikawa, Koji Shindo, Kohei Nakata, Taiki Moriyama, Yoshihiro Miyasaka, Takao Ohtsuka, Masafumi Nakamura
Abstract
AB081. P053 Survival of unresectable pancreatic cancer patients after artery divestment combined pancreatectomy: a retrospective and propensity score-matched analysis
Baobao Cai, Zipeng Lu, Kuirong Jiang, Junli Wu, Wentao Gao, Jianmin Chen, Feng Guo, Jishu Wei, Cuncai Dai, Yi Miao
Abstract
AB082. P054. Non-functional pancreatic neuroendocrine tumor (NF PNET) imaging and evaluation using 18F-FDG and 68Ga-DOTANOC-PET/CT: initial data of a prospective study
Hanna Seppanen, Susanna Majala, Jukka Kemppainen, Camilla Schalin-Jäntti, Risto Gullichsen, Johanna Arola, Saila Kauhanen
Abstract
AB083. P055. Total pancreatectomy in radical pancreatectomy for pancreatic cancer
Kuirong Jiang, Pengfei Wu, Zipeng Lu, Kai Zhang, Cuncai Dai, Junli Wu, Wentao Gao, Jianmin Chen, Jishu Wei, Feng Guo, Baobao Cai, Jie Yin, Dong Xu, Yi Miao
Abstract
AB084. P056. Intra-operative ultrasound to determine resectability during surgical exploration of primary nonresectable pancreatic cancer following induction chemotherapy
Marieke Walma, Eran van Veldhuisen, Bengt van Rijssen, Olivier Busch, Rutger Bruijnen, Otto van Delden, Nadia Haj Mohammad, Ignace de Hingh, Hanneke van Laarhoven, Maarten van Leeuwen, Yung Nio, Hjalmar van Santvoort, Johanna Verheij, Jan de Vries, Frank Wessels, Hanneke Wilmink, Quintus Molenaar, Marc Besselink, Krijn van Lienden
Abstract
AB085. P057. Early monocentric experience in EUS-FNA wettechnique for pancreatic lesions
Niccolò Furbetta, Dario Gambaccini, Gregorio Di Franco, Desirée Gianardi, Matteo Palmeri, Simone Guadagni, Matteo Bianchini, Jessica Bronzoni, Niccola Funel, Daniela Campani, Giulio Di Candio, Carlo Fabbri, Slavatore Russo, Giampaolo Bresci, Santino Marchi, Franco Mosca, Emanuele Marciano, Luca Morelli
Abstract
AB086. P058. Current status of pancreatic cystic neoplasm: diagnosis and treatment a multi-institution retrospective study in China
Yadong Xu, Ji Li, Xin Wang, Gang Li, Gang Zhao, Lei Wang, Jun Cao, Kuirong Jiang, Zheng Wang, Xueli Bai, Yongsheng Yang, Chunhui Yuan, Xiaodong Tian, Xiaowu Xu, Fabao Liu, Xue’e Bai, Rui Kong, Wenchuan Wu, Wenhui Lou
Abstract
AB087. P059. Strategy for radical dissection of two anatomical difficult triangles for pancreatic head cancer—laparoscopic pancreaticoduodenectomy with left uncinate first approach
Chunhua Xi, Wentao Gao, Min Tu, Haifeng Li, Cheng Lu, Kuirong Jiang, Junli Wu, Feng Guo, Jianmin Chen, Jishu Wei, Zipeng Lu, Cuncai Dai, Yi Miao
Abstract
AB088. P060. Safety assessment of standardized pancreatectomy in patients with solid pseudopapillary tumor and pancreatic ductal adenocarcinoma: retrospective case-control study in a single center
Peng Wang, Jishu Wei, Kai Zhang, Qiuyang Chen, Tongtai Liu, Junli Wu, Wentao Gao, Kuirong Jiang, Yi Miao
Abstract
AB089. P061. Pancreatectomies associated to vein resection: a large single institution experience
Robin Kivila, Roberto Valente, Elena Rangelova, Asif Halimi, Zeeshan Ateeb, Chiara Scandavini, Ralf Segersvard, Urban Arnelo, Marco Del Chiaro
Abstract
AB090. P062. Strategy of postoperative follow-up for intraductal papillary mucinous neoplasms
Ryohei Kobayashi, Seiko Hirono, Manabu Kawai, Ken-ichi Okada, Motoki Miyazawa, Yuji Kitahata, Masaki Ueno, Shinya Hayami, Norihiko Suzaki, Hiroki Yamaue
Abstract
AB091. P063. Case report: stage 4 pancreatic cancer to remission using paricalcitol and hydroxychloroquine in addition to traditional chemotherapy
Stephen Bigelsen
Abstract
AB092. P064. The preliminary experience of total or proximal intestinal derotation procedure applied in pancreatoduodenectomy
Wenchuan Wu, Lei Zhang, Nin Pu
Abstract
AB093. P066. Pancreaspreserving management of grade-c pancreatic fistulas after pancreaticoduodenectomy: a single center’s experience
Wenchuan Wu, Lei Zhang, Nin Pu
Abstract
AB094. P067. Therapeutic strategies and prognosis in patients with borderline resectable pancreatic adenocarcinoma: a multicenter retrospective study
Hiroshi Kurahara, Hiroyuki Shinchi, Takao Ohtsuka, Yoshihiro Miyasaka, Hirokazu Noshiro, Susumu Eguchi, Atsushi Nanashima, Hiroaki Nagano, Masafumi Inomata, Hideo Baba, Yulo Mataki, Kosei Maemura, Shoji Natsugoe, Masafumi Nakamura
Abstract
AB095. P069. Identification of therapeutic genomic alterations by investigating cancer-related genes and microsatellite instability: road to precision medicine for pancreatic ductal adenocarcinoma
Ding Ding, Ammar Javed, Dea Cunningham, Jonathan Teinor, Michael Wright, Chunhui Yuan, Cara Wilt, Amy Ryan, Carol Judkins, Keith McIntyre, Rachel Klein, Amy Hacker-Prietz, Eun Ji Shin, Atif Zaheer, Dung Le, Anne Marie Lennon, Mouen Kashab, Vikesh Singh, Jin He, Alex Blair, Vincent Groot, Jun Yu, Georgios Gemenetzis, Ross Donehower, Ana Jesus-Acosta, Adrian Murphy, John Cameron, Lindsey Manos, Christi Walsh, Lara Espin, Caitlin Brown, Tiffany Zavadsky, Matthew Weiss, Richard Burkhart, Nilo Azad, Amol Narang, Valerie Lee, Elizabeth Thompson, Elliot Fisherman, Robert Anders, Ralph Hruban, Elizabeth Jaffee, Christopher Wolfgang, Lei Zheng, Daniel Laheru, on behalf of Johns Hopkins Precision Medicine Program
Abstract
AB096. P070. Feasibility and efficacy of an analysis using FFPE blocks of resected pancreas with micro CT
Koji Shindo, Kenoki Ohuchida, Holger Roth, Hirohisa Oda, Chika Iwamoto, Masahiro Oda, Kensaku Mori, Makoto Hashizume, Masafumi Nakamura
Abstract
AB097. P071. Implications of the pattern of disease recurrence on survival following pancreatectomy for pancreatic ductal adenocarcinoma
Vincent P. Groot, Georgios Gemenetzis, Alex Blair, Ammar Javed, Richard Burkhart, Jun Yu, Inne Borel Rinkes, Quintus Molenaar, John Cameron, Elliot Fishman, Ralph Hruban, Matthew Weiss, Christopher Wolfgang, Jin He
Abstract
AB098. P072. Investigation of BRCAness in pancreatic cancer using patient-derived organoid models
Mohammed A. Al Efishat, Nicolas Lecomte, Gokce Askan, Rui Wang, Marc F Attiyeh, Pedro B. C. Albornoz, Jacklynn V. Egger, Liguo Zhang, Caitlin Jones, Cristian D. Cruz, Brian Herbst, Vicky Baudin, Tanisha Leach, Jerry P. Melchor, Robert Delsite, Nadeem Riaz, Kenneth H. Yu, Nicholas D. Socci, Peter J. Allen, Christine Iacobuzio-Donahue, Eileen M. O’Reilly, Steven D. Leach
Abstract
AB099. P073. Clinicopathological analysis of cystic pancreatic carcinoma in 31 cases
Chunhui Yuan, Lianyuan Tao, Xueying Shi, Ming Chen, Zhipeng Zhang, Ming Tao, Chen Ye, Qing Chen, Sadula Abuduhaibaier, Siqian Ren, Bin Jiang, Zhaolai Ma, Lei Ll, Ying Peng, Hangyan Wang, Lingfu Zhang, Dianrong Xiu, Tonglin Zhang
Abstract
AB100. P074. Novel biomarkers for differential diagnosis of intraductal papillary mucinous neoplasms revealed by profiling microbial composition and translocation markers in liquid biopsies
Rogier Gaiser, Haleh Davanian, Hassan Alkharaan, Carlos Fernández Moro, Zeeshan Ateeb, Marco Del Chiaro, Margaret Sällberg Chen
Abstract
AB101. P75. Surgical management of pancreatic neuroendocrine neoplasms (PNENs) in a single center
Junli Wu, Wenbin Xu, Jishu Wei, Kai Zhang, Xinchun Liu, Mingna Li, Zhihong Zhang, Yi Miao
Abstract
AB102. P076. Preoperative panel of CA 19-9, coagulation FVIII, fibrin turnover marker D-dimer and thrombin time predicts postoperative survival in pancreatic ductal adenocarcinoma
Hanna Seppänen, Nora Mattila, Riitta Lassila, Caj Haglund
Abstract
AB103. P077. Preoperative biomarker panel distinguishes PDAC from IPMN
Hanna Seppänen, Nora Mattila, Harri Mustonen, Caj Haglund, Riitta Lassila
Abstract
AB104. P078. Exosomal microRNAs in pancreatic juice have possibility as biomarkers to detect pancreatic ductal adenocarcinoma
So Nakamura, Yoshihiko Sadakari, Takafumi Okayama, Yohei Nakashima, Yoshitaka Gotoh, Yasuhisa Mori, Kohei Nakata, Yoshihiro Miyasaka, Takao Ohtsuka, Michael Goggins, Masafumi Nakamura
Abstract
AB105. P079. Impact of extravasated platelet activation surrounding cancer associated fibroblasts by neoadjuvant chemotherapy in pancreatic ductal adenocarcinoma
Tomoharu Miyashita, Hidehiro Tajima, Mitsuyoshi Okazaki, Yoshinao Ohbatake, Shinichi Nakanuma, Isamu Makino, Hiroyuki Takamura, John W. Harmon, Tetsuo Ohta
Abstract
AB106. P080. Interferon gamma-inducible protein 10 in pancreatic cancer progression
Veethika Pandey, Tam Le, Brandy Edenfield, Peter Storz
Abstract
AB107. P081. Metabolic oligosaccharide engineering of pancreatic cells: measurement of sialylation and identification of sialylated glycoproteins
Vrinda Dharmarha, Christopher Saeui, Jian Song, Hui Li, Howard Katz, Kevin Yarema
Abstract
AB108. P082. Role of epigenetic modifying enzymes in the chemoresistance of pancreatic cancer
Wen-Chun Hung, Ming-Chuan Hsu, Li-Tzong Chen
Abstract
AB109. P083. Low expression of KLF9 in pancreatic cancer and its correlation with tumor differentiations
Xiangbao Yin, Zhiwei Zhong, Fan Zhou, Dong Wang, Mingming Wu, Linquan Wu
Abstract
AB110. P084. OGDHL inhibits human pancreatic ductal adenocarcinoma progression and is regulated by microRNA-214/TWIST1 negative feedback pathway
Yao Liu, Lianxin Liu
Abstract
AB111. P085. The key factors related to the postoperative survival duration of patients with pancreatic ductal adenocarcinoma
Yatong Li, Menghua Dai
Abstract
AB112. P086. MicroRNA miR- 141/200c inhibit proliferation, invasion and metastasis of human pancreatic cancer cells by targeting WIPF1-YAP/TAZ pathway
Yu Pan, Fengchun Lu, Ping Xiong, Zheyang Zhan, Xianchao Lin, Heguang Huang
Abstract
AB113. P087. Single-cell sequencing defines genetic heterogeneity in pancreatic cancer precursor lesions
Yuko Kuboki, Cathy Guerra, Violeta Beleva, Wenjie Huang, Jun Yu, Peter Chianchiano, Waki Hosoda, Lily Zheng, Xiaoshan Shao, Elizabeth Thompson, Kevin Waters, Justin Poling, Jin He, Matthew Weiss, Christopher Wolfgang, Michael Goggins, Ralph Hruban, Nicholas Roberts, Rachel Karchin, Laura Wood
Abstract
AB114. P088. Comparison between robotic assisted and the ‘gold standard’ open approach for left sided cystic tumors of the pancreas: results from a single center
Gregorio Di Franco, Matteo Palmeri, Simone Guadagni, Niccolò Furbetta, Metteo Bianchini, Niccola Funel, Desirée Gianardi, Luca Pollina, Andrea Pietrabissa, Dario Gambaccini, Santino Marchi, Giulio Di Candio, Franco Mosca, Luca Morelli
Abstract
AB115. P089. Comparison of prognostic prediction between nomogram based on lymph node ratio and AJCC 8th staging system for patients with resected pancreatic head carcinoma: a SEER analysis
Ning Pu, Guochao Zhao, Abulimiti Nuerxiati, Hanlin Yin, Wenhui Lou, Wenchuan Wu
Abstract
AB116. P090. Preliminary results with laparoscopic pancreatoduodenectomy: a comparative series with open procedure in a single center
Omero da Costa Filho, Marcelo Lontra, Jose Olijnyk
Abstract
AB117. P092. Safety of intraoperative pancreatoscopy for the investigation of main pancreatic duct involvement and assessment of skip lesions in operated main duct (MD) involving IPMNs: a feasibility study
Roberto Valente, Urban Arnelo, Marcus Hansson, Zeeshan Ateeb, Elena Rangelova, Matthias Lohr, Raffaella Pozzi Mucelli, Marco Del Chiaro
Abstract
AB118. P093. Impact of neoadjuvant chemoradiotherapy using full-dose gemcitabine and concurrent radiation for resectable pancreatic cancer
Takahiro Akahori, Minako Nagai, Satoshi Nishiwada, Kenji Nakagawa, Kota Nakamura, Naoya Ikeda, Masayuki Sho
Abstract
AB119. P095. Organ preserving pancreatectomy for pancreatic benign or low-grade malignant tumor: a report of 66 cases in a single institution
Weidong Xiao, Shengrong Lin, Antao Wu, Jun Cai, Donghui Zheng, Yong Li
Abstract
AB120. P096. A new pancreatojejunostomy of ductto- mucosa combining “backto- back” cross horizontal mattress anastomosis reduce postoperative pancreatic fistula
Wen-Chuan Wu, Lei Zhang, Nin Pu
Abstract
AB120. P096. A new pancreatojejunostomy of ductto- mucosa combining “backto- back” cross horizontal mattress anastomosis reduce postoperative pancreatic fistula
Wen-Chuan Wu, Lei Zhang, Nin Pu
Abstract
AB120. P096. A new pancreatojejunostomy of ductto- mucosa combining “backto- back” cross horizontal mattress anastomosis reduce postoperative pancreatic fistula
Wen-Chuan Wu, Lei Zhang, Nin Pu
Abstract
AB121. P097. Retrospective comparison analysis between pathology and the fukuoka consensus in resected IPMN in a single center
Wentao Gao, Haifend Li, Min Tu, Chunhua Xi, Kuirong Jiang, Junli Wu, Feng Guo, Jianmin Chen, Jishu Wei, Zipeng Lu, Chen Lu, Cuncai Dai, Yi Miao
Abstract
AB122. P098. The effect of somatostatin analogues on postoperative outcomes following pancreatic surgery: a meta-analysis
Xianlin Han, Zhiyan Xu, Wenming Wu
Abstract
AB123. P099. Type 2 diabetes mellitus, a vital and independent risk factor for acute pancreatitis in patients with severe hypertriglyceridemia
Xiaole Zhu, Chaoqun Hou, Yunpeng Peng, Chenyuan Shi, Kai Zhang, Qiang Li, Yi Miao
Abstract
AB124. P100. The prevalence and characteristics of pancreatic solid pseudopapillary tumor associate with malignance: a multicenter retrospective study in China
Yadong Xu, Lei Wang, Gang Li, Xin Wang, Zheng Wang, Ji Li, Gang Zhao, Kuirong Jiang, Chunhui Yuan, Xueli Bai, Yongsheng Yang, Xiaodong Tian, Fubao Liu, Xiaowu Xu, Jun Cao, Xue’e Bai, Rui Kong, Wenhui Lou, Wenchuan Wu
Abstract
AB125. P101. Recurrence and survival after surgery for pancreatic cancer with or without acute pancreatitis
Yonghua Chen, Keyu Li, Xubao Liu
Abstract
AB126. P102. Clinicopathological feature of early-stage pancreatic cancer—tumor size was less than 10 mm
Yoshihiro Nakashima, Koji Yoshida
Abstract
AB127. P103. Evaluation of new stent for EUS-guided pancreatic duct drainage: longterm follow-up outcome
Yukitoshi Matsunami, Atsushi Sofuni, Takayoshi Tsuchiya, Reina Tanaka, Ryosuke Tonozuka, Shuntaro Mukai, Mitsuru Fujita, Kenjiro Yamamoto, Yasutsugu Asai, Takashi Kurosawa, Takao Itoi
Abstract
AB128. P104. Gemcitabine/ taxane adjuvant therapy with chemoradiation in resected pancreatic cancer: a novel strategy for improved survival?
Zaheer Kanji, Alicia Edwards, Margaret Mandelson, Nadav Sahar, Bruce Lin, Kasra Badiozamani, Guobin Song, Adnan Alseidi, Thomas Biehl, Richard Kozarek, Scott Helton, Vincent Picozzi, Favio Rocha
Abstract
AB129. P105. A comparative study of the totally onelayer and stratified pancreaticojejunostomy in pancreaticoduodenectomy
Tianhong Teng, Fengchun Lu, Xianchao Lin, Ronggui Lin, Shi Wen, Heguang Huang
Abstract
AB130. P106. Threedimensional visualization technology used in pancreatic surgery: a valuable tool for surgical trainees
Chen Lin, Junyi Gao, Hua Zheng, Jun Zhao, Hua Yang, Yue Zheng, Yihan Cao, Yufei Chen, Guoliang Wu, Guole Lin, Jianchun Yu, Hanzhong Li, Hui Pan, Quan Liao, Yupei Zhao
Abstract
AB131. P107. Prognostic value of preoperative nutritional and immunological factors in patients with pancreatic ductal adenocarcinoma
Toshiya Abe, Kohei Nakata, Shin Kibe, Yasuhisa Mori, Yoshihiro Miyasaka, Kenoki Ohuchida, Takao Ohtsuka, Y. Oda, Masafumi Nakamura
Abstract
AB132. P108. Intraoperative radiotherapy (IORT) followed by concurrent chemotherapy (CCRT) or stereotactic radiotherapy (SBRT) for locally advanced pancreatic cancer
Xu Che, Chengfeng Wang