Yadong Xu1, Ji Li1, Xin Wang2, Gang Li3, Gang Zhao4, Lei Wang5, Jun Cao6, Kuirong Jiang7, Zheng Wang8, Xueli Bai9, Yongsheng Yang10, Chunhui Yuan11, Xiaodong Tian12, Xiaowu Xu13, Fabao Liu14, Xue’e Bai15, Rui Kong15, Wenchuan Wu1, Wenhui Lou1
1Fudan University, Shanghai 200433, China;2Huaxi Hospital of Sichuan University, Chengdu 610041, China;3Second Military Medical University, Shanghai 200433, China;4Huazhong University of Science and Technology, Wuhan 430074, China;5Shandong University, Jinan 250100, China;6The Second Affiliated Hospital of Sun Yat-sen University, Guangzhou 510120, China;7The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China;8The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an 710061, China;9The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310009, China;10The Second Affiliated Hospital of Jilin University, Changchun 130041, China;11The Third Affiliated Hospital of Beijing University, Beijing 100191, China;12The First Affiliated Hospital of Beijing University, Beijing 100034, China;13The Peoples Hospital of Zhejiang Province, Hangzhou 310014, China;14The First Affiliated Hospital of Anhui Medical University, Hefei 230022, China;15The First Affiliated Hospital of Harbin Medical University, Harbin 150001, China
Background: The aims of this study were to introduce our current situation of diagnosis and treatment of pancreatic cystic neoplasm (PCN) in China.
Methods: A total of 2,251 PCN patients who underwent surgical resection from January 2006 to December 2016 in 16 institutions were retrospectively analyzed.
Results: The male to female ratio was 1 to 2.4, and the age at diagnosis was 47.5 years (range, 8–89 years). The preoperative diagnostic coincidence rate of solid pseudo-papillary tumor (SPT) was 48.5%, serous cystic neoplasm (SCN) was 13.7%, intraductal papillary mucinous neoplasm (IPMN) was 49.7, mucinous cystic neoplasm (MCN) was 15.6% respectively and the PCN was 33%. SPT, SCN, IPMN, MCN were 713 cases, 678 cases, 495 cases, 365 cases respectively by pathologically diagnosed, and the malignant transformation rate was 12.3%,0.6%,32.1%,10.4% respectively. The rate of postoperative complications was 46%, the pancreatic fistula (PF) and delayed gastric emptying (DGE) were the main complications. The tumor marker, such as CEA, CA19-9, CA125, was significantly increased in the malignant group.
Conclusions: SPT maybe the most common tumor in all PCN in China. Improving the accuracy of subtype (especially the SCN and the MCN) diagnosis preoperatively can avoid unnecessary surgery.
doi: 10.21037/apc.2018.AB086
