Yadong Xu1, Lei Wang2, Gang Li3, Xin Wang4, Zheng Wang5, Ji Li6, Gang Zhao7, Kuirong Jiang8, Chunhui Yuan9, Xueli Bai10, Yongsheng Yang11, Xiaodong Tian12, Fubao Liu13, Xiaowu Xu14, Jun Cao15, Xue’e Bai16, Rui Kong16, Wenhui Lou1, Wenchuan Wu1
1Zhongshan Hospital, Shanghai 200032, China;2Shandong University, Jinan 250100, China;3Changhai Hospital, Shanghai 200438, China;4Huaxi Hospital of Sichuan University, Chengdu 610041, China;5The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an 710061, China;6Huashan Hospital, Shanghai 200040, China; 7Huazhong University of Science and Technology, Wuhan 430074, China;8The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China;9The Third Affiliated Hospital of Beijing University, Beijing 100191, China;10The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310009, China;11The Second Affiliated Hospital of Jilin University, Changchun 130041, China; 12The First Affiliated Hospital of Beijing University, Beijing 100034, China;13The First Affiliated Hospital of Anhui Medical University, Hefei 230022, China;14The Peoples Hospital of Zhejiang Province, Hangzhou 310014, China;15The Second Affiliated Hospital of Sun Yat-sen University, Guangzhou 510120, China;16The First Affiliated Hospital of Haerbin Medical University, Harbin 150001, China
Background: The main aim of this study was to seek the clinical risk factors for malignance of pancreatic for solid pseudopapillary tumors (SPTs) in China.
Methods: Seven hundred five-four patients’ information included preoperative or postoperative for diagnostic SPTs were collected from the standardized reports from January 2008 to December 2015 in the 16 institutions. And 685 cases with complete information relatively which have preoperative diagnosis concurrently.
Results: Of the 754 patients, 88 (12.3%) cases were pathologically proved as malignant tumor. Of the 685 patients, 314 (45.8%) cases were diagnosed SPTs correctly before operation and 644 (94.0%) cases confirmed as SPTs by the pathological diagnosis. The mean age at diagnosis was 33.1 years and the tumor longest diameter greater than 3cm appear in 74.5% patients. 210 patients were subjected to postoperative pancreatic fistula (PF), and 4 cases experienced grade C PF. The clinical factors, such as sex (P=0.97), age (P=0.38), tumor location (P=0.45) and size (P=0.21), CA 19-9 lever (P=0.71), mural nodule (P=1), solid component (P=0.84), wall enhancement (P=0.66), calcification (P=0.18), were meaningless to judge the malignant SPTs before operation.
Conclusions: Maybe the regional discrepancy in distribution existed through the percentage of SPTs. There’s some room for improvement to make the right judgment for SPTs diagnosis in the preoperative. Evaluating the risk of the malignancy of SPTs still requires more accurate diagnostic criteria.
doi: 10.21037/apc.2018.AB124
